How To Improve Testosterone Gel Absorption

Patients have a number of options as it relates to testosterone replacement therapy delivery options. Testosterone gel is a popular option and improving testosterone gel absorption rates is an important consideration.

Testosterone gel is a medication used to treat low testosterone levels in men. It is applied to the skin and is absorbed through the skin into the bloodstream. However, there are several factors that can affect the absorption of testosterone gel, and it is important to optimize these factors to ensure that the medication is effective.

Apply the Gel on Clean and Dry Skin

One way to improve testosterone gel absorption is to apply the gel to clean, dry skin. The skin should be free of any lotions, oils, or other substances that can interfere with the absorption of the medication. It is also important to apply the gel to an area of skin that has a large surface area, such as the shoulders or upper arms.

testosterone gel absorption

Schedule Showering and Use the Correct Amount of Gel

Another way to improve testosterone gel absorption is to avoid showering or bathing for at least two hours after applying the gel. This will help to ensure that the medication is not washed off before it has had a chance to be absorbed.

It is also important to use the correct amount of testosterone gel. Using too much gel can lead to skin irritation and increased risk of side effects, while using too little can lead to inadequate treatment. The dose and frequency of testosterone gel use should be determined by a healthcare provider.

Rotate the Application Site of Testosterone Gel

It is also important to rotate the application site of testosterone gel. This is because applying the gel to the same site repeatedly can lead to skin irritation, and also the body can develop tolerance to the medication in that specific area.

Additionally, using a thinner layer of gel can also help improve absorption. Thicker layers of gel may not be absorbed as well, so it is important to apply the gel as thinly as possible.

Avoid Sun Exposure

Another important step to improve testosterone gel absorption is to avoid direct sun exposure to the application area. Sunlight can reduce the effectiveness of testosterone gel, and the skin should be protected by clothing or sunscreen.

In some cases, it may be helpful to use a skin enhancer or transdermal delivery system with the testosterone gel. These products can help to increase the absorption of the medication by increasing the amount of testosterone that is delivered to the bloodstream.

Finally, it is important to regularly monitor testosterone levels through blood tests to ensure that the medication is working properly. If testosterone levels are not increasing as expected, a healthcare provider may need to adjust the dose or frequency of testosterone gel use.


What is the best time to apply testosterone gel?
Testosterone gel is typically best applied in the morning, as this mimics the body’s natural testosterone rhythm. Applying it after a shower can also be effective, as the skin is clean and pores are more open.
Where should I apply testosterone gel for the best absorption?
It should be applied to clean, dry skin on areas like the shoulders, upper arms, or abdomen. Avoid applying it to areas with thick skin, like the soles of the feet or palms, as absorption may be less effective there.
Can I shower or swim after applying testosterone gel?
It’s advisable to wait at least a few hours before showering or swimming to ensure the gel has been fully absorbed. Check the instructions of the specific product for the best guidance.
Does sweating affect testosterone gel absorption?
Excessive sweating might affect absorption. Try to apply the gel at a time when you’re less likely to sweat heavily, and allow it to fully dry and absorb before engaging in activities that cause sweating.
How long does it take for testosterone gel to be absorbed?
This can vary, but typically, it takes a few hours for the gel to be fully absorbed. Avoid touching the area or letting others touch it during this time to prevent transfer.
Can I apply moisturizer or sunscreen over the testosterone gel?
It’s generally recommended to avoid applying other products over the area where the gel has been applied until it’s fully absorbed to prevent interference with absorption.
Are there any specific foods or supplements that improve testosterone gel absorption?
There’s no direct evidence suggesting that certain foods or supplements can improve absorption. However, maintaining overall good health, including a balanced diet, can support hormone balance and effectiveness.
Does the amount of body hair affect testosterone gel absorption?
Thick body hair might hinder absorption, so some people may choose to apply the gel to areas with less hair or even shave the area where the gel is applied.
How can I ensure consistent absorption of testosterone gel?
Apply the gel at the same time each day, ensure the skin is clean and dry, and follow the application instructions precisely. Consistency in application helps maintain steady absorption.
What should I do if I miss a dose of testosterone gel?
If you miss a dose, apply it as soon as you remember. However, if it’s close to the time for your next dose, skip the missed dose and resume your regular dosing schedule. Avoid doubling up on doses.


Improving testosterone gel absorption requires a combination of various factors such as applying the gel to clean, dry skin, avoiding showering or bathing for at least two hours after applying the gel, using the correct amount of gel, rotating the application site, using a thinner layer of gel, avoiding direct sun exposure, using a skin enhancer or transdermal delivery system, and monitoring testosterone levels regularly. Consulting with a healthcare provider is essential to achieve the best results.

If you have any additional questions about hormonal replacement therapy or need any advice related to your hormonal health, don’t hesitate to reach out to HRT Doctors Group and schedule a consultation for expert guidance and support in achieving a healthy hormonal balance!

Research Citations

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  • “Factors affecting the pharmacokinetics of testosterone delivered by a transdermal patch” by D.J. Handelsman, et al. (2000)
  • “Transdermal testosterone gel improves sexual function, mood, muscle strength, and body composition parameters in hypogonadal men” by S.J. Bhasin, et al. (2000)